Articles with "response bet" as a keyword



Abstract 6806: Deciphering the role of BRD2 in acute adaptive response to BET inhibitors across cancers

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-6806

Abstract: Bromodomain and extraterminal motif (BET) inhibitors, such as JQ1, are a promising therapeutic strategy against cancer, targeting key epigenetic regulators, particularly BRD4. However, resistance to BET inhibitors poses a significant challenge, necessitating a deeper understanding… read more here.

Keywords: cancer; brd2; response bet; bet inhibitors ... See more keywords