Deep Learning Based Radiomics Predicts Response to Chemotherapy in Colorectal Liver Metastases.
Sign Up to like & getrecommendations! Published in 2020 at "Medical physics"
DOI: 10.1002/mp.14563
Abstract: PURPOSE To develop and validate a deep learning (DL)-based radiomics model to predict the response to chemotherapy in colorectal liver metastases (CRLM). METHODS In this retrospective study, we enrolled 192 patients diagnosed with CRLM who… read more here.
Keywords: radiomics model; response chemotherapy; based radiomics; response ... See more keywords
Early assessment of response to chemotherapy in lung cancer using dynamic contrast-enhanced MRI: a proof-of-concept study.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical radiology"
DOI: 10.1016/j.crad.2018.02.013
Abstract: AIM To evaluate the early treatment response to chemotherapy in patients with lung cancer using dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). MATERIALS AND METHODS Twenty-two patients with lung cancer underwent DCE-MRI before chemotherapy and… read more here.
Keywords: chemotherapy; response chemotherapy; non responders; lung cancer ... See more keywords
Immune gene expression and response to chemotherapy in advanced breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.446
Abstract: Background:Transcriptomic profiles have shown promise as predictors of response to neoadjuvant chemotherapy in breast cancer (BC). This study aimed to explore their predictive value in the advanced BC (ABC) setting.Methods:In a Phase 3 trial of… read more here.
Keywords: chemotherapy; response chemotherapy; response; breast cancer ... See more keywords
Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy
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DOI: 10.1038/s41598-019-50848-z
Abstract: Extracellular vesicles (EVs) are emerging as key players in intercellular communication. EVs can transfer biological macromolecules to recipient cells, modulating various physiological and pathological processes. It has been shown that tumor cells secrete large amounts… read more here.
Keywords: extracellular vesicles; response chemotherapy; response; melanoma cells ... See more keywords
Predicting chemotherapy response using a variational autoencoder approach
Sign Up to like & getrecommendations! Published in 2021 at "BMC Bioinformatics"
DOI: 10.1186/s12859-021-04339-6
Abstract: Background Multiple studies have shown the utility of transcriptome-wide RNA-seq profiles as features for machine learning-based prediction of response to chemotherapy in cancer. While tumor transcriptome profiles are publicly available for thousands of tumors for… read more here.
Keywords: response chemotherapy; response; approach; cancer ... See more keywords
Comparative transcriptomic profiling of renal medullary carcinoma (RMC) to determine distinct signatures and pathways associated with response to chemotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.4575
Abstract: 4575Background: RMC is a highly aggressive renal cell carcinoma (RCC) with poor prognosis and variable response to chemotherapy. It is often treated with cytotoxic regimens used for collecting duct... read more here.
Keywords: response chemotherapy; rmc; carcinoma; comparative transcriptomic ... See more keywords
The effect of VEGF rs35569394 in esophageal cancer and response to chemotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Bosnian journal of basic medical sciences"
DOI: 10.17305/bjbms.2021.5891
Abstract: The objective of this study was to investigate the possible association between the single nucleotide polymorphism (SNP), rs35569394, of the vascular endothelial growth factor gene (VEGF) and the risk of esophageal cancer (EC) in the… read more here.
Keywords: vegf rs35569394; rs35569394; response chemotherapy;
Development of a model to predict pathologic response to chemotherapy in patients with colorectal liver metastases.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of gastrointestinal oncology"
DOI: 10.21037/jgo-21-82
Abstract: Background Preoperative chemotherapy has widely been used in colorectal cancer liver metastasis (CRLM). Pathological response to chemotherapy is very important in evaluating tumor biology. However, there is still a lack of a non-invasive and accurate… read more here.
Keywords: chemotherapy; response; preoperative chemotherapy; response chemotherapy ... See more keywords
Novel Non-Invasive Radiomic Signature on CT Scans Predicts Response to Platinum-Based Chemotherapy and Is Prognostic of Overall Survival in Small Cell Lung Cancer
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DOI: 10.3389/fonc.2021.744724
Abstract: Background Small cell lung cancer (SCLC) is an aggressive malignancy characterized by initial chemosensitivity followed by resistance and rapid progression. Presently, there are no predictive biomarkers that can accurately guide the use of systemic therapy… read more here.
Keywords: chemotherapy; ste; response chemotherapy; index ... See more keywords