Impact of pharmacogenomics upon the therapeutic response to etanercept in psoriasis and psoriatic arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2017.1361404
Abstract: ABSTRACT Introduction: TNF-α inhibitors have demonstrated efficacy both as monotherapy and in combination with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of chronic inflammatory immune-mediated diseases. Etanercept is a decoy receptor” for TNF-α and it… read more here.
Keywords: pharmacogenomics upon; tnf; response; impact pharmacogenomics ... See more keywords
AB0015 The effect of rare coding variants on response of tnf inhibitors treatment in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6862
Abstract: Background Although pharmacogenetic studies of TNF inhibitors (TNFi) response presented the estimates of high heritability, only few loci with suggestive weak common association as biomarkers for TNFi response have been identified. Objectives We aimed to… read more here.
Keywords: coding variants; response; rare coding; association ... See more keywords