Lesion of Serotonergic Afferents to the Retrotrapezoid Nucleus Impairs the Tachypneic Response to Hypercapnia in Unanesthetized Animals
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DOI: 10.1016/j.neuroscience.2020.11.005
Abstract: Hypercapnia promotes an increase in pulmonary ventilation due to the stimulation of brainstem chemosensory cells that are connected to the respiratory network. Among these cells are the raphe serotonergic neurons which widely send projections to… read more here.
Keywords: response; hypercapnia; response hypercapnia; serotonergic neurons ... See more keywords
Ventilatory Response to Hypercapnia as Experimental Model to Study Effects of Oxycodone on Respiratory Depression.
Sign Up to like & getrecommendations! Published in 2021 at "Current clinical pharmacology"
DOI: 10.2174/1574884716666210225083213
Abstract: BACKGROUND Opioid analgesics used to treat pain can cause respiratory depression. However, this effect has not been extensively studied, and life- threatening, opioid-induced respiratory depression remains difficult to predict. We tested the ventilatory response to… read more here.
Keywords: response hypercapnia; depression; ventilatory response; respiratory depression ... See more keywords