A Smart Responsive Fluorescence-MR Nanoprobe for Monitoring Tumor Response to Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300602
Abstract: Accurately evaluating tumor response to immunotherapy is clinically relevant. However, non-invasive, real-time visualization techniques to evaluate tumor immunotherapy are still lacking. Herein, we report a smart responsive fluorescence-MR dual-modal nanoprobe, QM(GP)-MZF(CP), that can be targeted… read more here.
Keywords: tumor response; smart responsive; immunotherapy; response immunotherapy ... See more keywords
Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.08.012
Abstract: Immunotherapy has revolutionized cancer treatment, yet most patients do not respond. Here, we investigated mechanisms of response by profiling the proteome of clinical samples from advanced stage melanoma patients undergoing either tumor infiltrating lymphocyte (TIL)-based… read more here.
Keywords: immunotherapy; response; melanoma response; proteomics melanoma ... See more keywords
A short-term follow-up CT based radiomics approach to predict response to immunotherapy in advanced non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2028962
Abstract: ABSTRACT To develop a short-term follow-up CT-based radiomics approach to predict response to immunotherapy in advanced non-small-cell lung cancer (NSCLC) and investigate the prognostic value of radiomics features in predicting progression-free survival (PFS) and overall… read more here.
Keywords: predict response; response immunotherapy; delta radiomics; radiomics model ... See more keywords
Complete response to immunotherapy in a nonagenarian patient with metastatic melanoma
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-235472
Abstract: Despite the increasing incidence of metastatic melanoma in the older population, there are relatively limited data for those older than 75 years of age. Elderly patients are often under-represented in clinical trials. In addition, elderly… read more here.
Keywords: melanoma; metastatic melanoma; immunotherapy nonagenarian; response immunotherapy ... See more keywords
Immunotherapy in stage IV non-small cell lung cancer in a patient with Grave’s disease: safety and biomarkers of response
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-245632
Abstract: Patients with cancer and pre-existing autoimmune diseases have been excluded from immunotherapy clinical trials. So, studying these patients who received immunotherapy is critical to increasing evidence of the treatment’s safety and efficacy in this population.… read more here.
Keywords: non small; immunotherapy; response immunotherapy; small cell ... See more keywords
Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-19-1744
Abstract: Purpose: Tumor genomic features have been of particular interest because of their potential impact on the tumor immune microenvironment and response to immunotherapy. Due to the substantial heterogeneity, an integrative approach incorporating diverse molecular features… read more here.
Keywords: immune microenvironment; immunotherapy; cancer; tumor ... See more keywords
Abstract 4435: A causal modeling platform for testing lifestyle interventions on the microbiome and response to immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4435
Abstract: Rational manipulation of the gut microbiome by diet or other interventions is a promising approach to improving the efficacy and safety of cancer immunotherapy. However, linking lifestyle variables to specific microbial populations and the host… read more here.
Keywords: response; response immunotherapy; intervention; tumor ... See more keywords
Radiotherapy may augment response to immunotherapy in metastatic uveal melanoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221131521
Abstract: Introduction: Uveal melanoma (UM) is a subtype of melanoma arising from the ocular region. Despite various local therapies available, a significant portion of patients develop distant metastases, primarily to the liver. While cutaneous melanoma is… read more here.
Keywords: immunotherapy; response immunotherapy; group; response ... See more keywords
Impressive response to immunotherapy in a metastatic gastric cancer patient: could somatic copy number alterations help patient selection?
Sign Up to like & getrecommendations! Published in 2017 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1186/s40425-017-0291-9
Abstract: Background Metastatic gastric cancer (GC) is an incurable and aggressive disease with a poor prognosis. Immunotherapy is an attractive approach for treating patients with cancer, and studies using immunotherapy have shown promising results in melanoma,… read more here.
Keywords: metastatic gastric; immunotherapy; gastric cancer; impressive response ... See more keywords
Frequency of genomic biomarkers of response to immunotherapy in sarcoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.11579
Abstract: 11579Background: Recent data (D’Angelo et al, 2018) has suggested possible benefit for a subset of sarcoma patients from immune checkpoint inhibitors (ICPI). We assessed a large sarcoma population ... read more here.
Keywords: sarcoma; frequency genomic; biomarkers response; genomic biomarkers ... See more keywords
Distinct cytokines predict response to immunotherapy and targeted therapy in metastatic renal cell carcinoma (mRCC).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.6_suppl.352
Abstract: 352Background: Previous studies have suggested a link between plasma cytokines and mRCC outcomes with systemic therapy. In a prospective study, we assessed whether plasma cytokines could separately... read more here.
Keywords: predict response; distinct cytokines; immunotherapy targeted; cytokines predict ... See more keywords