A Smart Responsive Fluorescence-MR Nanoprobe for Monitoring Tumor Response to Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300602
Abstract: Accurately evaluating tumor response to immunotherapy is clinically relevant. However, non-invasive, real-time visualization techniques to evaluate tumor immunotherapy are still lacking. Herein, we report a smart responsive fluorescence-MR dual-modal nanoprobe, QM(GP)-MZF(CP), that can be targeted… read more here.
Keywords: tumor response; smart responsive; immunotherapy; response immunotherapy ... See more keywords
Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
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DOI: 10.1016/j.cell.2019.08.012
Abstract: Immunotherapy has revolutionized cancer treatment, yet most patients do not respond. Here, we investigated mechanisms of response by profiling the proteome of clinical samples from advanced stage melanoma patients undergoing either tumor infiltrating lymphocyte (TIL)-based… read more here.
Keywords: immunotherapy; response; melanoma response; proteomics melanoma ... See more keywords
A short-term follow-up CT based radiomics approach to predict response to immunotherapy in advanced non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2028962
Abstract: ABSTRACT To develop a short-term follow-up CT-based radiomics approach to predict response to immunotherapy in advanced non-small-cell lung cancer (NSCLC) and investigate the prognostic value of radiomics features in predicting progression-free survival (PFS) and overall… read more here.
Keywords: predict response; response immunotherapy; delta radiomics; radiomics model ... See more keywords
BIOM-63. MOLECULAR FEATURES OF AGGRESSIVE MMR DEFICIENCY BRAIN TUMORS AND RESPONSE TO IMMUNOTHERAPY
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.0151
Abstract: Primary Brain tumors (PBT) can be divided in two macroscopic categories: glioma and non-glioma. They may harbor different molecular alterations, apart from the more classical in MGMT and IDH. MSI/dMMR status has been evaluated in… read more here.
Keywords: gliomas; brain tumors; response immunotherapy;
Complete response to immunotherapy in a nonagenarian patient with metastatic melanoma
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DOI: 10.1136/bcr-2020-235472
Abstract: Despite the increasing incidence of metastatic melanoma in the older population, there are relatively limited data for those older than 75 years of age. Elderly patients are often under-represented in clinical trials. In addition, elderly… read more here.
Keywords: melanoma; metastatic melanoma; immunotherapy nonagenarian; response immunotherapy ... See more keywords
Immunotherapy in stage IV non-small cell lung cancer in a patient with Grave’s disease: safety and biomarkers of response
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-245632
Abstract: Patients with cancer and pre-existing autoimmune diseases have been excluded from immunotherapy clinical trials. So, studying these patients who received immunotherapy is critical to increasing evidence of the treatment’s safety and efficacy in this population.… read more here.
Keywords: non small; immunotherapy; response immunotherapy; small cell ... See more keywords
Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-19-1744
Abstract: Purpose: Tumor genomic features have been of particular interest because of their potential impact on the tumor immune microenvironment and response to immunotherapy. Due to the substantial heterogeneity, an integrative approach incorporating diverse molecular features… read more here.
Keywords: immune microenvironment; immunotherapy; cancer; tumor ... See more keywords
Abstract 4435: A causal modeling platform for testing lifestyle interventions on the microbiome and response to immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4435
Abstract: Rational manipulation of the gut microbiome by diet or other interventions is a promising approach to improving the efficacy and safety of cancer immunotherapy. However, linking lifestyle variables to specific microbial populations and the host… read more here.
Keywords: response; response immunotherapy; intervention; tumor ... See more keywords
Radiotherapy may augment response to immunotherapy in metastatic uveal melanoma patients
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DOI: 10.1177/17588359221131521
Abstract: Introduction: Uveal melanoma (UM) is a subtype of melanoma arising from the ocular region. Despite various local therapies available, a significant portion of patients develop distant metastases, primarily to the liver. While cutaneous melanoma is… read more here.
Keywords: immunotherapy; response immunotherapy; group; response ... See more keywords
Predicting response to immunotherapy in oral squamous cell carcinoma via a CT-based radiomics model
Sign Up to like & getrecommendations! Published in 2024 at "BMC Medical Imaging"
DOI: 10.1186/s12880-024-01444-9
Abstract: To investigate whether radiomics models derived from pretreatment CT could help to predict response to immunotherapy in oral squamous cell carcinoma (OSCC). Retrospectively, a total of 40 patients with measurable OSCC were included. The patients… read more here.
Keywords: based radiomics; response; radiomics model; response immunotherapy ... See more keywords
The predictive value of intratumoral tertiary lymphoid structures on the response to immunotherapy in cancer patients: a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2025 at "BMC cancer"
DOI: 10.1186/s12885-025-15322-2
Abstract: An increasing number of studies have demonstrated tertiary lymphoid structures (TLS) was associated with prognosis and therapeutic response of immunotherapy in cancer patients. This meta-analysis aimed to investigate the predictive value of intratumoral TLS on… read more here.
Keywords: analysis; cancer; cancer patients; response immunotherapy ... See more keywords