Developmentally Regulated CYP2E1 Expression Is Associated with a Fetal Pulmonary Transcriptional Response to Maternal Acetaminophen Exposure
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DOI: 10.3390/biomedicines13102446
Abstract: Background/Objectives: Acetaminophen (APAP) is used during 50–60% of pregnancies in the U.S. and has been associated with childhood respiratory morbidity, though the underlying mechanism remains unclear. APAP-induced injury is dependent on cell-specific expression of CYP2E1,… read more here.
Keywords: cyp2e1 expression; apap; transcriptional response; response maternal ... See more keywords