Isoaspartate formation and irreversible aggregation of collapsin response mediator protein 2: implications for the etiology of epilepsy and age-related cognitive decline
Sign Up to like & getrecommendations! Published in 2024 at "Amino Acids"
DOI: 10.1007/s00726-024-03435-0
Abstract: Collapsin response mediator protein 2 (CRMP2) functions in the genesis and activity of neuronal connections in mammalian brain. We previously reported that a protein coincident with CRMP2 on 2D-gels undergoes marked accumulation of abnormal L-isoaspartyl… read more here.
Keywords: crmp2; etiology; collapsin response; response mediator ... See more keywords
Research Progress of Collapse Response Mediator Proteins in Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neuroscience"
DOI: 10.1159/000523875
Abstract: Collapse response mediator proteins (CRMPs) are a family of cytoplasmic phosphorylated proteins, and the mechanism of action has always been the research focus of neurological diseases. Previous studies on the CRMPs family have revealed that… read more here.
Keywords: collapse response; response mediator; mediator proteins; neurodegenerative diseases ... See more keywords
Identification of Anti-Collapsin Response Mediator Protein 2 Antibodies in Patients With Encephalitis or Encephalomyelitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.854445
Abstract: Background and Purpose An increasing number of autoimmune encephalitis (AE)-associated autoantibodies have been successfully characterized. However, many cases of AE remain unexplained on account of unknown antibodies. The aim of the present study was to… read more here.
Keywords: mediator protein; collapsin response; crmp2; response mediator ... See more keywords