Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19
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DOI: 10.1016/j.isci.2020.101896
Abstract: Dysregulated IL-1β and IL-6 responses have been implicated in the pathogenesis of severe Coronavirus Disease 2019 (COVID-19). Innovative approaches for evaluating the biological activity of these cytokines in vivo are urgently needed to complement clinical… read more here.
Keywords: response modules; modules characterize; covid; activity ... See more keywords
INfORM: Inference of NetwOrk Response Modules
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DOI: 10.1093/bioinformatics/bty063
Abstract: Summary: Detecting and interpreting responsive modules from gene expression data by using network‐based approaches is a common but laborious task. It often requires the application of several computational methods implemented in different software packages, forcing… read more here.
Keywords: network; response modules; inference network; inform inference ... See more keywords