A prospective cohort study of HLA-B44 supertype as predictor of response to novel immune checkpoint combinations.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e15071
Abstract: e15071Background: To date there are no clear predictors of response to novel immune checkpoint inhibitor (ICI) combinations. Recent reports suggest that HLA-I (Human Leukocyte Antigen Class I) supe... read more here.
Keywords: response novel; immune checkpoint; novel immune;
The Unfolded Protein Response—Novel Mechanisms, Challenges, and Key Considerations for Therapeutic Intervention
Sign Up to like & getrecommendations! Published in 2025 at "Cancers"
DOI: 10.3390/cancers17223639
Abstract: Simple Summary The unfolded protein response is an intricate network of pathways that mediates intracellular and intercellular cancer cell fate. Previous works have focused mainly on the intracellular roles of UPR. Through a systematic review… read more here.
Keywords: response novel; novel mechanisms; unfolded protein; protein response ... See more keywords
Host Immune Response and Novel Diagnostic Approach to NTM Infections
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21124351
Abstract: The incidence and prevalence of non-tuberculous mycobacteria (NTM) infections are steadily increasing worldwide, partially due to the increased incidence of immunocompromised conditions, such as the post-transplantation state. The importance of proper diagnosis and management of… read more here.
Keywords: response novel; host immune; novel diagnostic; immune response ... See more keywords
Polymorphisms Affecting the Response to Novel Antiepileptic Drugs
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032535
Abstract: Epilepsy is one of the most frequent chronic neurologic disorders that affects nearly 1% of the population worldwide, especially in developing countries. Currently, several antiepileptic drugs (AEDs) are available for its therapy, and although the… read more here.
Keywords: response novel; antiepileptic drugs; polymorphisms affecting; affecting response ... See more keywords
Microstructure and Friction Response of a Novel Eutectic Alloy Based on the Fe-C-Mn-B System
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DOI: 10.3390/ma15249031
Abstract: This paper focuses on the microstructure and tribological properties of novel hardfacing alloy based on Fe-C-Mn-B doped with Ni, Cr, and Si. The 4 mm-thick coating was deposited on the AISI 1045 carbon steel by… read more here.
Keywords: friction response; response novel; friction; alloy based ... See more keywords