Expression, Purification, and Characterization of the Recombinant, Two-Component, Response Regulator ArlR from Fusobacterium nucleatum
Sign Up to like & getrecommendations! Published in 2022 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-021-03785-5
Abstract: Fusobacterium nucleatum is associated with the incidence and development of multiple diseases, such as periodontitis and colorectal cancer (CRC). Until now, studies have proved only a few proteins to be associated with such pathogenic diseases.… read more here.
Keywords: response regulator; expression; nucleatum; expression purification ... See more keywords
Improved tolerance of Escherichia coli to oxidative stress by expressing putative response regulator homologs from Antarctic bacteria
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microbiology"
DOI: 10.1007/s12275-020-9290-5
Abstract: Response regulator (RR) is known a protein that mediates cell’s response to environmental changes. The effect of RR from extremophiles was still under investigation. In this study, response regulator homologs were mined from NGS data… read more here.
Keywords: response regulator; response; tolerance; regulator homologs ... See more keywords
The DNA-binding mechanism of the TCS response regulator ArlR from Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2019.09.005
Abstract: ArlRS is an essential two-component system in Staphylococcus aureus that regulates the transcription of virulence factors and participate in numerous pathogenic and symbiotic processes. In this work, we identified different DNA binding properties and oligomerization… read more here.
Keywords: response regulator; staphylococcus aureus; mechanism; dna ... See more keywords
A tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling†
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d0sc06226j
Abstract: Pseudomonas aeruginosa is a difficult-to-treat Gram-negative bacterial pathogen causing life-threatening infections. Adaptive resistance (AR) to cationic peptide antibiotics such as polymyxin B impairs the therapeutic success. This self-protection is mediated by two component systems (TCSs)… read more here.
Keywords: response regulator; pseudomonas aeruginosa; interkingdom signaling; probe ... See more keywords
Real-time detection of response regulator phosphorylation dynamics in live bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2201204119
Abstract: Significance Bacteria use two-component systems (TCSs) to sense and adapt to the environment. The core process of TCS signaling involves a sensor histidine kinase (SHK) phosphorylating or dephosphorylating a response regulator (RR) in a stimulus-gated… read more here.
Keywords: response; live bacteria; response regulator; real time ... See more keywords
Cytokinin-inducible response regulator SlRR6 regulates plant height through gibberellin and auxin pathways in tomato.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of experimental botany"
DOI: 10.1093/jxb/erad159
Abstract: Plant height is a key agronomic trait regulated by several phytohormones like gibberellins (GAs) and auxin. However, little is known about how cytokinin (CK) participates in this process. Here, we report that SlRR6, a type-A… read more here.
Keywords: plant height; response regulator; slrr6; plant ... See more keywords
Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1164
Abstract: Abstract The RcsCDB phosphorelay system controls an extremely large regulon in Enterobacteriaceae that involves processes such as biofilm formation, flagella production, synthesis of extracellular capsules and cell division. Therefore, fine-tuning of this system is essential… read more here.
Keywords: response regulator; rcsb; dynamism; conformational dynamism ... See more keywords
Xanthomonas campestris sensor kinase HpaS co‐opts the orphan response regulator VemR to form a branched two‐component system that regulates motility
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.12901
Abstract: Abstract Xanthomonas campestris pv. campestris (Xcc) controls virulence and plant infection mechanisms via the activity of the sensor kinase and response regulator pair HpaS/hypersensitive response and pathogenicity G (HrpG). Detailed analysis of the regulatory role… read more here.
Keywords: response regulator; response; hpas; sensor kinase ... See more keywords
Response Regulator CD1688 Is a Negative Modulator of Sporulation in Clostridioides difficile
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00130-22
Abstract: Clostridioides difficile causes severe gastrointestinal illness and is a leading cause of nosocomial infections in the United States. This pathogen produces metabolically dormant spores that are the major vehicle of transmission between hosts. ABSTRACT Two-component… read more here.
Keywords: clostridioides difficile; sporulation; cd1688; response regulator ... See more keywords
The Histidine Kinase CckA Is Directly Inhibited by a Response Regulator-like Protein in a Negative Feedback Loop
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DOI: 10.1128/mbio.01481-22
Abstract: The two-component systems (TCS) in bacteria in its simplest architecture consist of a histidine kinase (HK) and a response regulator (RR). In response to a specific stimulus, the HK is activated and drives phosphorylation of… read more here.
Keywords: response regulator; response; histidine kinase; ccka ... See more keywords
Overexpression, purification, crystallization and preliminary X-ray crystallographic characterization of the receiver domain of the response regulator PhoP from Enterococcus faecalis ATCC 29212
Sign Up to like & getrecommendations! Published in 2019 at "Applied Biological Chemistry"
DOI: 10.1186/s13765-019-0473-x
Abstract: Phosphate (Pho) regulon plays a critical role in bacterial phosphate homeostasis. It is regulated by two-component system (TCS) that comprises a sensor histidine kinase and transcriptional response regulator (RR). PhoP from Enterococcus faecalis (EfPhoP) belongs… read more here.
Keywords: response regulator; regulator phop; enterococcus faecalis; phop enterococcus ... See more keywords