Expression, Purification, and Characterization of the Recombinant, Two-Component, Response Regulator ArlR from Fusobacterium nucleatum
Sign Up to like & getrecommendations! Published in 2022 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-021-03785-5
Abstract: Fusobacterium nucleatum is associated with the incidence and development of multiple diseases, such as periodontitis and colorectal cancer (CRC). Until now, studies have proved only a few proteins to be associated with such pathogenic diseases.… read more here.
Keywords: response regulator; expression; nucleatum; expression purification ... See more keywords
Improved tolerance of Escherichia coli to oxidative stress by expressing putative response regulator homologs from Antarctic bacteria
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microbiology"
DOI: 10.1007/s12275-020-9290-5
Abstract: Response regulator (RR) is known a protein that mediates cell’s response to environmental changes. The effect of RR from extremophiles was still under investigation. In this study, response regulator homologs were mined from NGS data… read more here.
Keywords: response regulator; response; tolerance; regulator homologs ... See more keywords
The DNA-binding mechanism of the TCS response regulator ArlR from Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2019.09.005
Abstract: ArlRS is an essential two-component system in Staphylococcus aureus that regulates the transcription of virulence factors and participate in numerous pathogenic and symbiotic processes. In this work, we identified different DNA binding properties and oligomerization… read more here.
Keywords: response regulator; staphylococcus aureus; mechanism; dna ... See more keywords
Expression and functional divergence of a type-A response regulator paralog pair formed by dispersed duplication during Populus deltoides evolution
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-07091-8
Abstract: Gene duplication and divergence are essential to plant evolution. The Arabidopsis type-A response regulator (ARR) family, negative regulators in cytokinin signaling, exemplifies gene expansion and differential retention. Despite extensive research, the understanding of type-A RR… read more here.
Keywords: response regulator; populus deltoides; duplication; divergence ... See more keywords
A tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling†
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d0sc06226j
Abstract: Pseudomonas aeruginosa is a difficult-to-treat Gram-negative bacterial pathogen causing life-threatening infections. Adaptive resistance (AR) to cationic peptide antibiotics such as polymyxin B impairs the therapeutic success. This self-protection is mediated by two component systems (TCSs)… read more here.
Keywords: response regulator; pseudomonas aeruginosa; interkingdom signaling; probe ... See more keywords
Real-time detection of response regulator phosphorylation dynamics in live bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2201204119
Abstract: Significance Bacteria use two-component systems (TCSs) to sense and adapt to the environment. The core process of TCS signaling involves a sensor histidine kinase (SHK) phosphorylating or dephosphorylating a response regulator (RR) in a stimulus-gated… read more here.
Keywords: response; live bacteria; response regulator; real time ... See more keywords
The response regulator FpsR controls the flagella-pili transition and mucosal colonization in Ligilactobacillus ruminis.
Sign Up to like & getrecommendations! Published in 2025 at "Gut microbes"
DOI: 10.1080/19490976.2025.2596807
Abstract: Abstract Ligilactobacillus ruminis is a flagellated lactic acid bacterium found in the intestines of various mammals, including humans. Although this species harbors a complete flagellar gene cluster, flagella formation has not been observed in human-derived… read more here.
Keywords: colonization; ligilactobacillus ruminis; ruminis; response regulator ... See more keywords
Cytokinin-inducible response regulator SlRR6 regulates plant height through gibberellin and auxin pathways in tomato.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of experimental botany"
DOI: 10.1093/jxb/erad159
Abstract: Plant height is a key agronomic trait regulated by several phytohormones like gibberellins (GAs) and auxin. However, little is known about how cytokinin (CK) participates in this process. Here, we report that SlRR6, a type-A… read more here.
Keywords: plant height; response regulator; slrr6; plant ... See more keywords
Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1164
Abstract: Abstract The RcsCDB phosphorelay system controls an extremely large regulon in Enterobacteriaceae that involves processes such as biofilm formation, flagella production, synthesis of extracellular capsules and cell division. Therefore, fine-tuning of this system is essential… read more here.
Keywords: response regulator; rcsb; dynamism; conformational dynamism ... See more keywords
Xanthomonas campestris sensor kinase HpaS co‐opts the orphan response regulator VemR to form a branched two‐component system that regulates motility
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.12901
Abstract: Abstract Xanthomonas campestris pv. campestris (Xcc) controls virulence and plant infection mechanisms via the activity of the sensor kinase and response regulator pair HpaS/hypersensitive response and pathogenicity G (HrpG). Detailed analysis of the regulatory role… read more here.
Keywords: response regulator; response; hpas; sensor kinase ... See more keywords
Xanthomonas oryzae Orphan Response Regulator EmvR Is Involved in Virulence, Extracellular Polysaccharide Production and Cell Motility
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.70083
Abstract: ABSTRACT Bacteria have evolved a large number of two‐component signalling systems (TCSs), which are typically composed of a histidine sensor kinase (HK) and a response regulator (RR), to sense environmental changes and modulate subsequent adaptive… read more here.
Keywords: response regulator; production cell; virulence; virulence extracellular ... See more keywords