Predicting critical drug concentrations and torsadogenic risk using a multiscale exposure-response simulator.
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DOI: 10.1016/j.pbiomolbio.2018.10.003
Abstract: Torsades de pointes is a serious side effect of many drugs that can trigger sudden cardiac death, even in patients with structurally normal hearts. Torsadogenic risk has traditionally been correlated with the blockage of a… read more here.
Keywords: risk; exposure response; response simulator; torsadogenic risk ... See more keywords