Modeling heterogeneous signaling dynamics of macrophages reveals principles of information transmission in stimulus responses
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-60901-3
Abstract: Macrophages initiate pathogen-appropriate immune responses with the activation dynamics of transcription factor NFκB mediating specificity. Live-cell imaging revealed the stimulus-response specificity of NFκB dynamics among populations of heterogeneous cells. To study stimulus-response specificity beyond what… read more here.
Keywords: stimulus response; information; response; response specificity ... See more keywords