Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-214877
Abstract: Objectives We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness… read more here.
Keywords: loci; response; association; response tnf ... See more keywords
Linking MAPK inhibition and the response to TNF in melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e24143
Abstract: e24143Background: Antigen presentation plays a central role in anti-tumor immunity and the response to immunotherapy. Recent studies have underscored the importance of MHC class I (MHC I) and class... read more here.
Keywords: response; linking mapk; mapk inhibition; inhibition response ... See more keywords
YAP Transcriptional Activity Dictates Cell Response to TNF In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.856247
Abstract: YAP/TAZ are transcription co-factors recently described responsive to pro-inflammatory cytokines and involved in inflammatory-related disorders. However, the role of tumor necrosis factor (TNF), a major pro-inflammatory cytokine, on YAP signaling is not well understood and… read more here.
Keywords: yap transcriptional; response tnf; response; transcriptional activity ... See more keywords