Predicting Probability of Response to Tumor Necrosis Factor Inhibitors for Individual Patients With Ankylosing Spondylitis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.2312
Abstract: Key Points Question Is it possible to predict short-term treatment response to tumor necrosis factor inhibitors (TNFis) accurately in patients with active ankylosing spondylitis (AS)? Findings In a cohort study of individual participant data from… read more here.
Keywords: necrosis factor; response tumor; tumor necrosis; factor inhibitors ... See more keywords
Tumor extracellular vesicles loaded with exogenous Let-7i and miR-142 can modulate both immune response and tumor microenvironment to initiate a powerful anti-tumor response.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.11.014
Abstract: Despite recent advances in cancer immunotherapy, there have been limitations in cancer treatment and patient survival due to a lack of antigen recognition and immunosuppressive tumor microenvironment. To overcome this issue, we have shown that… read more here.
Keywords: extracellular vesicles; response; cancer; tumor microenvironment ... See more keywords
Humoral factors in serum as predictors of therapeutic response to tumor necrosis factor inhibitors in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.15413
Abstract: This study aimed to evaluate the predictive value of serum humoral factors in determining the therapeutic responses to biologic DMARDs (bDMARDs), especially TNF inhibitors (TNFis), in patients with RA. read more here.
Keywords: response tumor; predictors therapeutic; humoral factors; therapeutic response ... See more keywords
Abstract LB083: Decoding systemic circadian regulation across multi-tissues in response to tumor stress
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-lb083
Abstract: Emerging evidence suggests that tumors produce molecular signals to subvert and perturb circadian-regulated immune system functions. Elucidating the mechanisms of tumor-mediated circadian disruption will promote the development of new therapies targeting tumor remote regulatory abilities.… read more here.
Keywords: tumor stress; tumor; regulation; response tumor ... See more keywords
The systemic immune-inflammation index is an independent predictor of survival for metastatic colorectal cancer and its association with the lymphocytic response to the tumor
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-018-1638-9
Abstract: BackgroundSystemic inflammation and immune dysfunction has been proved to be significantly associated with cancer progression and metastasis in many cancer types, including colorectal cancer. We examined the prognostic significance of the systemic immune-inflammation index (SII)… read more here.
Keywords: sii; lymphocytic response; colorectal cancer; cancer ... See more keywords
Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment
Sign Up to like & getrecommendations! Published in 2025 at "Genome Medicine"
DOI: 10.1186/s13073-025-01511-y
Abstract: Monocytes are recruited to tumors and undergo transcriptional reprogramming resulting in tumor-promoting functions. Epigenomic features, such as post-translational modification of histones and chromatin accessibility, are key determinants of transcription factor binding and thereby play an… read more here.
Keywords: peripheral monocytes; response tumor; preconditioning peripheral; tumor microenvironment ... See more keywords
Editorial: The role of angiogenesis and immune response in tumor microenvironment of solid tumor
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1195390
Abstract: COPYRIGHT © 2023 Guo, Jiang, Ou, Lu, Cheng and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums… read more here.
Keywords: response tumor; editorial role; role angiogenesis; immune response ... See more keywords
FLIM of NAD(P)H in Lymphatic Nodes Resolves T-Cell Immune Response to the Tumor
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415829
Abstract: Assessment of T-cell response to the tumor is important for diagnosis of the disease and monitoring of therapeutic efficacy. For this, new non-destructive label-free methods are required. Fluorescence lifetime imaging (FLIM) of metabolic coenzymes is… read more here.
Keywords: flim nad; response tumor; immune response; tumor ... See more keywords