Ventilatory responses to hypoxic and hypercapnic environments in naked mole‐rats
Sign Up to like & getrecommendations! Published in 2023 at "Acta Physiologica"
DOI: 10.1111/apha.13963
Abstract: Extreme environments are powerful drivers of physiological adaptation. Naked mole‐rats offer an informative example of this relationship as they putatively encounter intermittent hypoxia and hypercapnia in their subterranean habitat. This has presumably driven the evolution… read more here.
Keywords: ventilatory responses; naked mole; mole rats; hypoxia hypercapnia ... See more keywords
Reciprocal role of PLAP-1 in HIF-1α-mediated responses to hypoxia.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontal research"
DOI: 10.1111/jre.12976
Abstract: OBJECTIVE To investigate the mutual regulation of hypoxia-inducible factor (HIF)-1α activity and periodontal ligament-associated protein-1 (PLAP-1) expression in human periodontal ligament cells (HPDLs). BACKGROUND Cellular responses to hypoxia regulate various biological events (e.g., inflammation and… read more here.
Keywords: hif; responses hypoxia; plap expression; plap ... See more keywords
Novel oxygen sensing mechanism in the spinal cord involved in cardiorespiratory responses to hypoxia
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm1444
Abstract: As blood oxygenation decreases (hypoxemia), mammals mount cardiorespiratory responses, increasing oxygen to vital organs. The carotid bodies are the primary oxygen chemoreceptors for breathing, but sympathetic-mediated cardiovascular responses to hypoxia persist in their absence, suggesting… read more here.
Keywords: mechanism; cardiorespiratory responses; spinal cord; oxygen ... See more keywords