Type I interferon signaling deficiency results in dysregulated innate immune responses to SARS‐CoV‐2 in mice
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202249913
Abstract: SARS‐CoV‐2 is a newly emerged coronavirus, causing the global pandemic of respiratory coronavirus disease (COVID‐19). The type I interferon (IFN) pathway is of particular importance for anti‐viral defense and recent studies identified that type I… read more here.
Keywords: ifn; innate immune; responses sars; type interferon ... See more keywords
Antibody responses against SARS‐CoV‐2 in COVID‐19 patients
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26241
Abstract: Abstract The emerging coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has become a global pandemic, and brings formidable challenges to public health, society and the economy worldwide. Currently, the… read more here.
Keywords: covid patients; cov covid; virology; responses sars ... See more keywords
Adaptive immune responses to SARS-CoV-2
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DOI: 10.1016/j.addr.2021.02.009
Abstract: This review focuses on adaptive immune responses against SARS-CoV-2, the coronavirus that causes COVID-19. A great deal of work has been accomplished in a very short period of time to describe adaptive immune responses and… read more here.
Keywords: adaptive immune; responses sars; infection; immune responses ... See more keywords
What do we know about the antibody responses to SARS-CoV-2?
Sign Up to like & getrecommendations! Published in 2021 at "Immunobiology"
DOI: 10.1016/j.imbio.2021.152054
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However,… read more here.
Keywords: responses sars; antibody; sars cov; know antibody ... See more keywords
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-21155-x
Abstract: The dynamics, duration, and nature of immunity produced during SARS-CoV-2 infection are still unclear. Here, we longitudinally measured virus-neutralising antibody, specific antibodies against the spike (S) protein, receptor-binding domain (RBD), and the nucleoprotein (N) of… read more here.
Keywords: cell responses; responses sars; antibody; months infection ... See more keywords
Robust immune responses to SARS-CoV-2 in a pediatric patient with B-Cell ALL receiving tisagenlecleucel
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2022.2035864
Abstract: Abstract Recipients of anti-CD19 targeted therapies such as chimeric antigen receptor (CAR)-T cell are considered at high risk for complicated Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) infection due to prolonged B cell aplasia and immunosuppression.… read more here.
Keywords: cell; tisagenlecleucel; immune responses; patient ... See more keywords
A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2073131
Abstract: ABSTRACT Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and associated clinical sequelae requires well-coordinated metabolic and immune responses that limit viral spread and promote recovery of damaged systems. However, the role of… read more here.
Keywords: responses sars; immune metabolic; sars cov; gut microbiota ... See more keywords
T cell and antibody responses to SARS‐CoV‐2: Experience from a French transplantation and hemodialysis center during the COVID‐19 pandemic
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16348
Abstract: Immunosuppressed organ‐transplanted patients are considered at risk for severe forms of COVID‐19. Moreover, exaggerated innate and adaptive immune responses might be involved in severe progression of the disease. However, no data on the immune response… read more here.
Keywords: cell antibody; responses sars; sars cov; cell ... See more keywords
Assessment of humoral and cellular immune responses to SARS CoV‐2 vaccination (BNT162b2) in immunocompromised renal allograft recipients
Sign Up to like & getrecommendations! Published in 2022 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13813
Abstract: Assessing the composition of immune responses to SARS‐CoV‐2 vaccines is critical for our understanding of protective immunity, especially for immune compromised patients. The Pfizer (BNT162b2) vaccination showed >90% efficacy in protecting individuals from infection. However,… read more here.
Keywords: vaccination; immune responses; assessment humoral; responses sars ... See more keywords
T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.165111
Abstract: Immune responses in people with multiple sclerosis (pwMS) on disease-modifying therapies (DMTs) have been of significant interest throughout the COVID-19 pandemic. Lymphocyte-targeting immunotherapies including anti-CD20 treatments and sphingosine-1-phosphate receptor (S1PR) modulators attenuate antibody responses after… read more here.
Keywords: cell responses; multiple sclerosis; vaccination; responses sars ... See more keywords
Low neutralizing antibody responses against SARS-CoV-2 in older patients with myeloma after the first BNT162b2 vaccine dose
Sign Up to like & getrecommendations! Published in 2021 at "Blood"
DOI: 10.1182/blood.2021011904
Abstract: Patients with multiple myeloma (MM) are at an increased risk for infection because of their immunocompromised state, old age, and comorbidities. Coronavirus disease 2019 (COVID-19) causes moderate to severe acute respiratory dysfunction in 77% of… read more here.
Keywords: low neutralizing; responses sars; cov older; neutralizing antibody ... See more keywords