Non-hematopoietic tryptophan metabolism is a driver of ineffective T cell responses during secondary pulmonary bacterial infection.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of immunology"
DOI: 10.1093/jimmun/vkaf197
Abstract: Pulmonary infections often fail to produce long-lived immune memory and the underlying mechanism(s) for this are unclear. Given the complex interactions between cells within the lung, we predicted intrinsic and extrinsic factors contribute to development… read more here.
Keywords: bacterial infection; responses secondary; cell; pulmonary bacterial ... See more keywords
Antigen (Ag) spread after sipuleucel-T and correlation with overall survival (OS): A real-world experience.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e16504
Abstract: e16504 Background: Sipuleucel-T is an autologous cellular immunotherapy for asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer. In IMPACT (NCT00065442), a phase 3 trial, sipuleucel-T-induced immune responses against target Ag prostatic acid phosphatase (PAP) or… read more here.
Keywords: sipuleucel; spread; responses secondary; real world ... See more keywords