A Tumor Microenvironment Model of Pancreatic Cancer to Elucidate Responses toward Immunotherapy
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DOI: 10.1002/adhm.202201907
Abstract: Pancreatic cancer is a devastating malignancy with minimal treatment options. Standard‐of‐care therapy, including surgery and chemotherapy, is unsatisfactory, and therapies harnessing the immune system have been unsuccessful in clinical trials. Resistance to therapy and disease… read more here.
Keywords: pancreatic cancer; tumor microenvironment; responses toward; tumor ... See more keywords
Valuing high arousal negative states increases negative responses toward outgroups across cultures.
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DOI: 10.1037/emo0001101
Abstract: Previous research demonstrates that the more people experience anger, fear, and other high arousal negative states (HAN) on average, the more prejudice and harm they express toward outgroups. Here we demonstrate that valuing HAN-above and… read more here.
Keywords: negative states; arousal negative; negative responses; toward outgroups ... See more keywords
Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours
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DOI: 10.1038/s41467-018-07603-1
Abstract: Tumours often evade CD8 T-cell immunity by downregulating TAP. T-cell epitopes associated with impaired peptide processing are immunogenic non-mutated neoantigens that emerge during tumour immune evasion. The preprocalcitonin (ppCT)16–25 neoepitope belongs to this category of… read more here.
Keywords: cell responses; peptide; responses toward; antigen ... See more keywords
Responses Toward Injustice Shaped by Justice Sensitivity – Evidence From Germany
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DOI: 10.3389/fpsyg.2022.858291
Abstract: Anger, indignation, guilt, rumination, victim compensation, and perpetrator punishment are considered primary responses associated with justice sensitivity (JS). However, injustice and high JS may predispose to further responses. We had N = 293 adults rate… read more here.
Keywords: responses toward; injustice; toward injustice; justice sensitivity ... See more keywords
The impact of public responses toward healthcare workers on their work engagement and well-being during the Covid-19 pandemic
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DOI: 10.3389/fpsyg.2022.949153
Abstract: Introduction/context Healthcare workers (HCWs) play an important role in fighting against the COVID-19 pandemic. However, they have been exposed to mixed public responses more significantly during the COVID-19 pandemic, which have potentially affected their work… read more here.
Keywords: work engagement; responses toward; covid pandemic; engagement well ... See more keywords