Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers.
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DOI: 10.1016/j.celrep.2019.07.047
Abstract: Maternal antibodies (MatAbs) protect offspring from infections but limit their responses to vaccination. The mechanisms of this inhibition are still debated. Using murine early-life immunization models mimicking the condition prevailing in humans, we observed the induction… read more here.
Keywords: cell repertoire; maternal antibodies; early life; responses vaccination ... See more keywords