Human dendritic cells activated with MV130 induce Th1, Th17 and IL‐10 responses via RIPK2 and MyD88 signalling pathways
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747024
Abstract: Recurrent respiratory tract infections (RRTIs) are the first leading cause of community‐ and nosocomial‐acquired infections. Antibiotics remain the mainstay of treatment, enhancing the potential to develop antibiotic resistances. Therefore, the development of new alternative approaches… read more here.
Keywords: signalling pathways; responses via; dendritic cells; th1 th17 ... See more keywords
IL‐33‐matured dendritic cells promote Th17 cell responses via IL‐1&bgr; and IL‐6
Sign Up to like & getrecommendations! Published in 2017 at "Cytokine"
DOI: 10.1016/j.cyto.2017.07.022
Abstract: Graphical abstract Figure. No Caption available. HighlightsIL33 enhances Th17 cell differentiation through DC maturation.IL33 does not directly induce differentiation of naïve CD4+ T cells to Th17 cells.IL33‐matDCs increase surface molecule‐expressions driving T cell activation.IL33‐matDCs promote… read more here.
Keywords: cell responses; bgr; responses via; th17 cell ... See more keywords
Prolactin Regulates Pain Responses via a Female-Selective Nociceptor-Specific Mechanism
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DOI: 10.1016/j.isci.2019.09.039
Abstract: Summary Many clinical and preclinical studies report an increased prevalence and severity of chronic pain among females. Here, we identify a sex-hormone-controlled target and mechanism that regulates dimorphic pain responses. Prolactin (PRL), which is involved… read more here.
Keywords: mechanism; prolactin regulates; responses via; female selective ... See more keywords
Enhanced Antitumor Immune Responses via a Self-Assembled Carrier-Free Nanovaccine.
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DOI: 10.1021/acs.nanolett.1c00648
Abstract: Nanovaccines have emerged as promising agents for cancer immunotherapy. However, insufficient antitumor immunity caused by inefficient antigen/adjuvant loading and complicated preparation processes are the major obstacles that limit their clinical application. Herein, two adjuvants, monophosphatidyl… read more here.
Keywords: immune responses; enhanced antitumor; via self; responses via ... See more keywords
The therapeutic implications of activated immune responses via the enigmatic immunoglobulin D.
Sign Up to like & getrecommendations! Published in 2021 at "International reviews of immunology"
DOI: 10.1080/08830185.2020.1861265
Abstract: Immunoglobulin D (IgD) is an enigmatic antibody and the least appreciated member of the immunoglobulin (Ig) family. Since its discovery over half a century ago, the essence of its function in the immune system has… read more here.
Keywords: immunoglobulin; immune responses; antibody; igd ... See more keywords