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Published in 2021 at "Science Signaling"
DOI: 10.1126/scisignal.abc4479
Abstract: Weakening autoinhibition of the kinase ZAP70 leads to overactive T cells and autoimmune disease. Stronger responses to weak ligands The protein tyrosine kinase ZAP70 links activated T cell antigen receptors (TCRs) to downstream signaling pathways.…
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Keywords:
responses weak;
r360p mutation;
zap70;
cell ... See more keywords