Pyruvate-responsive genetic circuits for dynamic control of central metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Nature Chemical Biology"
DOI: 10.1038/s41589-020-0637-3
Abstract: Dynamic regulation is a promising strategy for fine-tuning metabolic fluxes in microbial cell factories. However, few of these synthetic regulatory systems have been developed for central carbon metabolites. Here we created a set of programmable… read more here.
Keywords: pyruvate responsive; genetic circuits; central metabolism; responsive genetic ... See more keywords
Harnessing flavonoids to control probiotic function: in situ application of a naringenin-responsive genetic circuit
Sign Up to like & getrecommendations! Published in 2025 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02890-24
Abstract: ABSTRACT Efforts to improve probiotics’ capabilities through synthetic biology have recently increased. Using naturally occurring plant-based compounds, such as flavonoids, as inputs of genetic circuits introduced in probiotics is a promising strategy to enhance or… read more here.
Keywords: responsive genetic; circuit; genetic circuit; genetic circuits ... See more keywords