Biomolecule‐Responsive Hydrogels in Medicine
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201700801
Abstract: Recent advances and applications of biomolecule-responsive hydrogels, namely, glucose-responsive hydrogels, protein-responsive hydrogels, and nucleic-acid-responsive hydrogels are highlighted. However, achieving the ultimate purpose of using biomolecule-responsive hydrogels in preclinical and clinical areas is still at the… read more here.
Keywords: biomolecule responsive; responsive hydrogels; hydrogels medicine;
Local delivery of bone morphogenetic protein-2 from near infrared-responsive hydrogels for bone tissue regeneration.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119909
Abstract: Achievement of spatiotemporal control of growth factors production remains a main goal in tissue engineering. In the present work, we combined inducible transgene expression and near infrared (NIR)-responsive hydrogels technologies to develop a therapeutic platform… read more here.
Keywords: near infrared; tissue; bone; bone morphogenetic ... See more keywords
Post-synthesis modification of thermo-responsive hydrogels: Hydrazone crosslinking of α-oxoaldehyde obtained from NIPAm-based polymers
Sign Up to like & getrecommendations! Published in 2019 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2019.01.028
Abstract: Abstract Currently, the chemistry of alpha-oxoaldehydes (α-oxo-ALD) is a versatile and useful tool in the field of bioconjugation of peptides and proteins. The combination of smart materials with biomolecules also represents an important opportunity for… read more here.
Keywords: oxo ald; responsive hydrogels; thermo responsive;
Waterborne pH responsive hydrogels: Synthesis, characterization and selective pH responsive behavior around physiological pH
Sign Up to like & getrecommendations! Published in 2019 at "Polymer"
DOI: 10.1016/j.polymer.2019.121701
Abstract: Abstract – pH responsive hydrogels, which selectively show highest swelling capacity around physiological pH (∼7.4) compared to both acidic and basic pH, are not known. In the current work, such hydrogels are prepared using one… read more here.
Keywords: swelling capacity; responsive hydrogels; responsive behavior; around physiological ... See more keywords
Stimuli-responsive hydrogels for manipulation of cell microenvironment: From chemistry to biofabrication technology
Sign Up to like & getrecommendations! Published in 2019 at "Progress in Polymer Science"
DOI: 10.1016/j.progpolymsci.2019.101147
Abstract: Abstract Native tissues orchestrate their functions by complex interdependent cascades of biochemical and biophysical cues that vary spatially and temporally during cellular processes. Scaffolds with well-tuned structural, mechanical, and biochemical properties have been developed to… read more here.
Keywords: responsive hydrogels; stimuli responsive; manipulation cell; cell ... See more keywords
Redox-Responsive Hydrogels for Tunable and "On-Demand" Release of Biomacromolecules.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00094
Abstract: In recent years, stimuli-responsive degradation has emerged as a desirable design criterion for functional hydrogels to tune the release of encapsulated payload as well as ensure degradation of the gel upon completion of its function.… read more here.
Keywords: degradation; demand release; redox responsive; responsive hydrogels ... See more keywords
Smart Structures—Additive Manufacturing of Stimuli-Responsive Hydrogels for Adaptive Packings
Sign Up to like & getrecommendations! Published in 2020 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.0c03137
Abstract: Smart materials possess a high potential for application in process engineering. Among these smart materials, stimuli-responsive hydrogels exhibit the chemically inherent characteristic to signific... read more here.
Keywords: manufacturing stimuli; smart structures; stimuli responsive; responsive hydrogels ... See more keywords
Oxidation of 8-thioguanosine gives redox-responsive hydrogels and reveals intermediates in a desulfurization pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc02926b
Abstract: A disulfide made by oxidation of 8-thioguanosine is a supergelator. The hydrogels are redox-responsive, as they disassemble upon either reduction or oxidation of the S-S bond. We also identified this disulfide, and 2 other compounds,… read more here.
Keywords: oxidation thioguanosine; redox responsive; thioguanosine gives; responsive hydrogels ... See more keywords
Dual-responsive hydrogels based on maleilated curdlan-graft-poly(N-isopropylacrylamide)
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Polymeric Materials and Polymeric Biomaterials"
DOI: 10.1080/00914037.2017.1417289
Abstract: ABSTRACT The esterification reaction between curdlan and maleic anhydride was performed to provide polymerizable double bonds and pH-sensitive carboxylic groups for the curdlan chains. The new derivative was used as macromolecular cross-linker in the polymerization… read more here.
Keywords: dual responsive; based maleilated; hydrogels based; maleilated curdlan ... See more keywords
Magneto-Responsive Hydrogels: Preparation, Characterization, Biotechnological and Environmental Applications
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Brazilian Chemical Society"
DOI: 10.21577/0103-5053.20190074
Abstract: Hydrogels are hydrophilic three-dimensional networks able to hold large amount of water and hydrophilic molecules. Magneto-responsive hydrogels comprise of magnetic nanoparticles dispersed in polymeric networks that can be manipulated under external magnetic field. This review… read more here.
Keywords: magneto responsive; responsive hydrogels; preparation characterization; applications magneto ... See more keywords
Pharmacokinetic Profile of Oxaliplatin-Loaded pH-Responsive Hydrogels in Rabbits.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical design"
DOI: 10.2174/1381612826666200813125159
Abstract: BACKGROUND Oxaliplatin (OXP), a 3rd generation platinum compound, is administered intravenously which causes severe side effects due to; impulse high concentration in the bloodstream thereby exposing healthy cells at a high ratio, non-specific delivery at… read more here.
Keywords: profile oxaliplatin; hematology; histopathology; pharmacokinetic profile ... See more keywords