Tumor Therapy Strategies Based on Microenvironment-specific Responsive Nanomaterials.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300153
Abstract: The tumor microenvironment (TME) is a complex and variable region characterized by hypoxia, low pH, high redox status, overexpression of enzymes, and high-ATP concentrations. In recent years, with the continuous in-depth study of nanomaterials, more… read more here.
Keywords: responsive nanomaterials; tumor therapy; therapy; based microenvironment ... See more keywords
Macromolecular Crowding as an Intracellular Stimulus for Responsive Nanomaterials.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c03064
Abstract: Stimuli-responsive materials are exploited in biological, materials, and sensing applications. We introduce a new endogenous stimulus, biomacromolecule crowding, which we achieve by leveraging changes in thermoresponsive properties of polymers upon high concentrations of crowding agents.… read more here.
Keywords: responsive nanomaterials; stimulus responsive; macromolecular crowding; crowding intracellular ... See more keywords
Hypoxia-responsive nanomaterials for tumor imaging and therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1089446
Abstract: Hypoxia is an important component of tumor microenvironment and plays a pivotal role in cancer progression. With the distinctive physiochemical properties and biological effects, various nanoparticles targeting hypoxia had raised great interest in cancer imaging,… read more here.
Keywords: responsive nanomaterials; tumor imaging; therapy; hypoxia responsive ... See more keywords
Recent Advance in Biological Responsive Nanomaterials for Biosensing and Molecular Imaging Application
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031923
Abstract: In recent decades, as a subclass of biomaterials, biologically sensitive nanoparticles have attracted increased scientific interest. Many of the demands for physiologically responsive nanomaterials in applications involving the human body cannot be met by conventional… read more here.
Keywords: responsive nanomaterials; molecular imaging; biosensing molecular; recent advance ... See more keywords