Chondroitin sulfate-based redox-responsive nanoparticles for melanoma-targeted drug delivery
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102033
Abstract: Abstract The therapeutic efficacy of most chemotherapeutic drugs is hampered by low water solubility, poor stability, serious side effects, and lack of tumor selectivity. To solve these issues, chondroitin sulfate (CS)-based redox-responsive nanoparticles were developed.… read more here.
Keywords: redox responsive; based redox; responsive nanoparticles; sulfate based ... See more keywords
Synergistic Chemo-Immunotherapy Using pH-Responsive Nanoparticles in Breast Cancer Treatment: In Vitro and In Vivo Studies.
Sign Up to like & getrecommendations! Published in 2024 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.4c00723
Abstract: Recent research underscores the pivotal role of the heterogeneous multicellular interactome within the tumor microenvironment (TME) in tumor progression and survival. Tumor-associated macrophages (TAMs), among other nonmalignant cells in the TME, promote an immunosuppressive environment,… read more here.
Keywords: chemo immunotherapy; breast cancer; immunotherapy using; tumor ... See more keywords
K+-Responsive Nanoparticles with Charge Reversal and Gating Synergistic Effects for Targeted Intracellular Bacteria Eradication.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.4c12542
Abstract: Intracellular bacteria can evade the attack of the immune system and the bactericidal effects of most antibiotics due to the protective effect of the host cells. Herein, inspired by the stimuli-responsive behaviors of biological ion… read more here.
Keywords: nanoparticles charge; gating synergistic; intracellular bacteria; reversal gating ... See more keywords
Light-Activated Hypoxia-Responsive Nanoparticles for Photodynamic Chemotherapy
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.4c11283
Abstract: Hypoxia is a characteristic of solid tumors, and it significantly impedes cancer treatment. Here, we report light-activated hypoxia-responsive nanoparticles NPs-TPZ consisting of 5,10,5,20-tetrakis(4-aminophenyl)-porphine (TAPP) modified with four azobenzene groups, cyclodextrin (CD), and 3-aminobenzotriazine-1,4-di-N-oxide tirapazamine (TPZ)… read more here.
Keywords: light activated; photodynamic chemotherapy; activated hypoxia; responsive nanoparticles ... See more keywords
Glutathione-responsive Nanoparticles for Optimized Cas9/sgRNA Gene Editing Delivery.
Sign Up to like & getrecommendations! Published in 2025 at "Current drug targets"
DOI: 10.2174/0113894501370119250409074208
Abstract: read more here.
Keywords: optimized cas9; glutathione responsive; nanoparticles optimized; cas9 sgrna ... See more keywords
Electromagnetically Stimuli-Responsive Nanoparticles-Based Systems for Biomedical Applications: Recent Advances and Future Perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Nanomaterials"
DOI: 10.3390/nano11040848
Abstract: Nanoparticles (NPs) in the biomedical field are known for many decades as carriers for drugs that are used to overcome biological barriers and reduce drug doses to be administrated. Some types of NPs can interact… read more here.
Keywords: based systems; responsive nanoparticles; electromagnetically stimuli; stimuli responsive ... See more keywords
pH-Responsive Nanoparticles for Delivery of Paclitaxel to the Injury Site for Inhibiting Vascular Restenosis
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030535
Abstract: A high incidence of restenosis has been reported at the site of inflammation following angioplasty and stent implantation. The anti-proliferative drug paclitaxel (PTX) could help to reduce inflammation and restenosis; however, it has poor water… read more here.
Keywords: responsive nanoparticles; restenosis; ptx nahco3; site ... See more keywords
Tumor Microenvironment-Based Stimuli-Responsive Nanoparticles for Controlled Release of Drugs in Cancer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14112346
Abstract: With the development of nanomedicine technology, stimuli-responsive nanocarriers play an increasingly important role in antitumor therapy. Compared with the normal physiological environment, the tumor microenvironment (TME) possesses several unique properties, including acidity, high glutathione (GSH)… read more here.
Keywords: stimuli responsive; responsive nanoparticles; release drugs; therapy ... See more keywords
Influence of the Polymer Microstructure over the Phase Separation of Thermo-Responsive Nanoparticles
Sign Up to like & getrecommendations! Published in 2021 at "Polymers"
DOI: 10.3390/polym13071032
Abstract: Thermo-responsive nanoparticles (NPs), i.e., colloids with a sharp and often reversible phase separation in response to thermal stimuli, are coming to the forefront due to their dynamic behavior, useful in applications ranging from biomedicine to… read more here.
Keywords: influence polymer; responsive nanoparticles; phase separation; thermo responsive ... See more keywords