Responsive neurostimulation targeting anterior thalamic nucleus in generalized epilepsy
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DOI: 10.1002/acn3.50858
Abstract: Responsive neurostimulation (RNS) has emerged as an adjunctive treatment modality for patients with intractable focal epilepsy who are not surgical candidates or have more than one ictal onset focus. We report a 34‐year‐old patient with… read more here.
Keywords: neurostimulation targeting; anterior thalamic; responsive neurostimulation; generalized epilepsy ... See more keywords
Centromedian thalamic responsive neurostimulation for Lennox‐Gastaut epilepsy and autism
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DOI: 10.1002/acn3.51173
Abstract: The RNS System is not approved in patients under 18, although a critical need for novel treatment modalities in this vulnerable population persist. We present two pediatric patients with drug‐resistant epilepsy secondary to Lennox‐Gastaut Syndrome… read more here.
Keywords: epilepsy; autism; lennox gastaut; responsive neurostimulation ... See more keywords
The Efficacy, Safety and Outcomes of Brain-responsive Neurostimulation (RNS® System) therapy in older adults.
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsia open"
DOI: 10.1002/epi4.12541
Abstract: Responsive neurostimulation is approved in patients above 18 years of age with drug resistant focal epilepsy. We aimed to investigate whether RNS outcomes and safety varied based on age. We included patients who had been… read more here.
Keywords: age; safety; younger adults; responsive neurostimulation ... See more keywords
Implantation of Responsive Neurostimulation for Epilepsy Using Intraoperative Computed Tomography: Technical Nuances and Accuracy Assessment.
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DOI: 10.1016/j.wneu.2017.03.136
Abstract: INTRODUCTION Implantation of responsive neurostimulation (RNS) system has been previously discussed in the literature but there is a paucity of data on target accuracy and the use of intraoperative imaging. We describe our experience with… read more here.
Keywords: implantation responsive; computed tomography; responsive neurostimulation; using intraoperative ... See more keywords
Robotic-Guided Bihippocampal and Biparahippocampal Depth Placement for Responsive Neurostimulation in Bitemporal Lobe Epilepsy.
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DOI: 10.1016/j.wneu.2017.10.164
Abstract: BACKGROUND Patients with bitemporal lobe epilepsy are generally not considered for surgical resection. Fortunately, responsive neurostimulation provides another avenue for the management of this challenging disease process. In conjunction with our epileptologist, we consider responsive… read more here.
Keywords: epilepsy; lobe epilepsy; bitemporal lobe; responsive neurostimulation ... See more keywords
Responsive Neurostimulation of the Thalamus Improves Seizure Control in Idiopathic Generalized Epilepsy: A Case Report.
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DOI: 10.1093/neuros/nyaa001
Abstract: BACKGROUND AND IMPORTANCE At least 25% of patients with idiopathic generalized epilepsy do not obtain adequate seizure control with medication. This report describes the first use of responsive neurostimulation (RNS), bilaterally targeting the centromedian/ventrolateral (CM/VL)… read more here.
Keywords: epilepsy; idiopathic generalized; responsive neurostimulation; seizure control ... See more keywords
Real-World Preliminary Experience With Responsive Neurostimulation in Pediatric Epilepsy: A Multicenter Retrospective Observational Study.
Sign Up to like & getrecommendations! Published in 2021 at "Neurosurgery"
DOI: 10.1093/neuros/nyab343
Abstract: BACKGROUND Despite the well-documented utility of responsive neurostimulation (RNS, NeuroPace) in adult epilepsy patients, literature on the use of RNS in children is limited. OBJECTIVE To determine the real-world efficacy and safety of RNS in… read more here.
Keywords: epilepsy; reduction; real world; pediatric epilepsy ... See more keywords
Operative Technique and Lessons Learned From Surgical Implantation of the NeuroPace Responsive Neurostimulation® System in 57 Consecutive Patients.
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DOI: 10.1093/ons/opaa300
Abstract: BACKGROUND The Responsive Neurostimulation (RNS)® System (NeuroPace, Inc) is an implantable device designed to improve seizure control in patients with medically refractory focal epilepsy. Because it is relatively new, surgical pearls and operative techniques optimized… read more here.
Keywords: system; responsive neurostimulation; technique lessons; implantation ... See more keywords
Early detection rate changes from a brain‐responsive neurostimulation system predict efficacy of newly added antiseizure drugs
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DOI: 10.1111/epi.16412
Abstract: Brain‐responsive neurostimulation (RNS System, NeuroPace) is used to treat medically refractory focal epilepsy and also provides long‐term ambulatory neurophysiologic data. We sought to determine whether these data could predict the clinical response to antiseizure drugs… read more here.
Keywords: system; antiseizure drugs; brain responsive; responsive neurostimulation ... See more keywords
Patient‐specific structural connectivity informs outcomes of responsive neurostimulation for temporal lobe epilepsy
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DOI: 10.1111/epi.17298
Abstract: Responsive neurostimulation is an effective therapy for patients with refractory mesial temporal lobe epilepsy. However, clinical outcomes are variable, few patients become seizure‐free, and the optimal stimulation location is currently undefined. The aim of this… read more here.
Keywords: temporal lobe; responsive neurostimulation; lobe epilepsy;
Anterior nucleus of the thalamus deep brain stimulation vs temporal lobe responsive neurostimulation for temporal lobe epilepsy
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DOI: 10.1111/epi.17331
Abstract: Based on the promising results of randomized controlled trials, deep brain stimulation (DBS) and responsive neurostimulation (RNS) are used increasingly in the treatment of patients with drug‐resistant epilepsy. Drug‐resistant temporal lobe epilepsy (TLE) is an… read more here.
Keywords: lobe; lobe epilepsy; temporal lobe; deep brain ... See more keywords