Immune Responsive Release of Tacrolimus to Overcome Organ Transplant Rejection.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201805018
Abstract: Transplant rejection is the key problem in organ transplantation and, in clinic, immunosuppressive agents such as tacrolimus are directly administered to the recipients after surgery for T-cell inhibition. However, direct administration of tacrolimus may bring… read more here.
Keywords: release tacrolimus; responsive release; rejection; immune responsive ... See more keywords
Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121554
Abstract: The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today. Different dosage forms - including films - for vaginal administration of antiretroviral drugs have been developed for… read more here.
Keywords: responsive release; bilayer films; release; eudragit l100 ... See more keywords
Preparation of magnetic microgels based on dextran for stimuli-responsive release of doxorubicin
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Magnetism and Magnetic Materials"
DOI: 10.1016/j.jmmm.2020.167394
Abstract: Abstract Hydrogel nanocomposites incorporated with magnetic nanoparticles (MNPs) were widely researched as promising candidate for environment-responsive drug delivery, due to their unique magnetic properties and quick response to an external magnetic field. In this study,… read more here.
Keywords: magnetic microgels; drug; responsive release; magnetic field ... See more keywords
Biomineralization inspired synthesis of CaCO3-based DDS for pH-responsive release of anticancer drug
Sign Up to like & getrecommendations! Published in 2021 at "Materials today communications"
DOI: 10.1016/j.mtcomm.2021.102256
Abstract: Abstract Calcium carbonate (CaCO3) is an ideal candidate for use in drug delivery system (DDS) for cancer cure due to good biocompatibility, pH-sensitivity and low-toxicity. However, developing a method that is fast and green, and… read more here.
Keywords: biomineralization; caco3; drug; based dds ... See more keywords
Facile Coordination-Precipitation Route to Insoluble Metal Roussin's Black Salts for NIR-Responsive Release of NO for Anti-Metastasis.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b11325
Abstract: A facile and general coordination-precipitation method is developed to synthesize insoluble metal Roussin's black salts (Me-RBSs) as a new type of NIR-responsive NORMs. The weak-field ligand coordination of metal+-RBS- brings a NIR absorption effect of… read more here.
Keywords: metal; nir responsive; coordination precipitation; responsive release ... See more keywords
A Self-Immolative Linker for the pH-Responsive Release of Amides
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28062445
Abstract: The administration of therapeutics using bioconjugation has been mainly limited to drugs containing amine, alcohol, or thiol functional groups. Here, we report a general procedure for the preparation of benzylic N-acyl carbamates suitable for masking… read more here.
Keywords: immolative linker; linker responsive; release amides; self immolative ... See more keywords