Reactive oxygen species-responsive RNA interference.
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DOI: 10.1039/d2cc00651k
Abstract: Due to oxidative instability, arylboronic acids are not compatible with the solid-phase synthesis of nucleic acids. We solved this problem and, based on these findings, developed siRNA prodrugs activated in the presence of reactive oxygen… read more here.
Keywords: responsive rna; rna interference; species responsive; oxygen species ... See more keywords