Articles with "responsiveness braf" as a keyword



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Differential responsiveness to BRAF inhibitors of melanoma cell lines BRAF V600E-mutated

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Published in 2020 at "Journal of Translational Medicine"

DOI: 10.1186/s12967-020-02350-8

Abstract: Background Most mutations in melanoma affect one critical amino acid on BRAF gene, resulting in the V600E substitution. Patient management is often based on the use of specific inhibitors targeting this mutation. Methods DNA and… read more here.

Keywords: braf v600e; cell lines; braf; responsiveness braf ... See more keywords