A REST Paradox: Does it Control or Enhance Neural Activity?
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DOI: 10.1177/15357597221081582
Abstract: The repressor-element 1-silencing transcription/neuron-restrictive silencer factor (REST/NRSF) controls hundreds of neuronspecific genes. We showed that REST/NRSF downregulates glutamatergic transmission in response to hyperactivity, thus contributing to neuronal homeostasis. However, whether GABAergic transmission is also implicated… read more here.
Keywords: inhibition; rest; paradox control; rest paradox ... See more keywords