Hepatic damage caused by long-term high cholesterol intake induces a dysfunctional restorative macrophage population in experimental NASH
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DOI: 10.3389/fimmu.2022.968366
Abstract: Excessive dietary cholesterol is preferentially stored in the liver, favoring the development of nonalcoholic steatohepatitis (NASH), characterized by progressive hepatic inflammation and fibrosis. Emerging evidence indicates a critical contribution of hepatic macrophages to NASH severity.… read more here.
Keywords: cholesterol intake; hepatic damage; restorative macrophage; high cholesterol ... See more keywords