Articles with "restores proteostasis" as a keyword



Mn(II) Quinoline Complex (4QMn) Restores Proteostasis and Reduces Toxicity in Experimental Models of Huntington’s Disease

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23168936

Abstract: Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder, of the so-called minority diseases, due to its low prevalence. It is caused by an abnormally long track of glutamines (polyQs) in mutant huntingtin (mHtt), which… read more here.

Keywords: restores proteostasis; huntington disease; quinoline complex; 4qmn restores ... See more keywords