Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes
Sign Up to like & getrecommendations! Published in 2018 at "Nature Medicine"
DOI: 10.1038/s41591-018-0203-7
Abstract: Identifying immunodominant T cell epitopes remains a significant challenge in the context of infectious disease, autoimmunity, and immuno-oncology. To address the challenge of antigen discovery, we developed a quantitative proteomic approach that enabled unbiased identification… read more here.
Keywords: antigen discovery; immunodominance; restricted epitopes; cell ... See more keywords
In silico analyses and experimental validation of the MHC class-I restricted epitopes of Ebolavirus GP.
Sign Up to like & getrecommendations! Published in 2022 at "International immunology"
DOI: 10.1093/intimm/dxac006
Abstract: Ebolavirus (EBOV) causes an extremely high mortality and prevalence disease called Ebola virus disease (EVD). There is only one glycoprotein (GP) on the virus particle surface, which mediates entry into the host cell. MHC class-I… read more here.
Keywords: class; restricted epitopes; class restricted; mhc class ... See more keywords