Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties.
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DOI: 10.1021/acs.molpharmaceut.8b00764
Abstract: The prostaglandin E2 receptor, EP2, plays an important role in physiology and in a variety of pathological conditions. Studies indicate that EP2 is pro-inflammatory in chronic peripheral and central nervous system disease and cancer models.… read more here.
Keywords: anti inflammatory; peripherally restricted; restricted highly; inflammatory ... See more keywords