Articles with "restricted phosphopeptide" as a keyword



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MHC-restricted phosphopeptide antigens: preclinical validation and first-in-humans clinical trial in participants with high-risk melanoma

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Published in 2020 at "Journal for Immunotherapy of Cancer"

DOI: 10.1136/jitc-2019-000262

Abstract: Background Phosphorylated peptides presented by MHC molecules represent a new class of neoantigens expressed on cancer cells and recognized by CD8 T-cells. These peptides are promising targets for cancer immunotherapy. Previous work identified an HLA-A*0201-restricted… read more here.

Keywords: trial participants; clinical trial; trial; pbcar3126 134 ... See more keywords