Diverse Host and Restriction Factors Regulate Mosquito-Pathogen Interactions.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in parasitology"
DOI: 10.1016/j.pt.2018.04.011
Abstract: Mosquitoes transmit diseases that seriously impact global human health. Despite extensive knowledge of the life cycles of mosquito-borne parasites and viruses within their hosts, control strategies have proven insufficient to halt their spread. An understanding… read more here.
Keywords: host restriction; restriction factors; diverse host; regulate mosquito ... See more keywords
A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68934-y
Abstract: Cell-derived influenza vaccines provide better protection and a host of other advantages compared to the egg-derived vaccines that currently dominate the market, but their widespread use is hampered by a lack of high yield, low… read more here.
Keywords: vaccine production; cell; host; restriction factors ... See more keywords
Genome-Scale Analysis of Cellular Restriction Factors That Inhibit Transgene Expression from Adeno-Associated Virus Vectors
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01948-22
Abstract: Recombinant AAV (rAAV) vectors have been successfully developed for the treatment of genetic diseases. The therapeutic strategy often involves the replacement of a defective gene by the expression of a functional copy from the rAAV… read more here.
Keywords: adeno associated; expression; transgene expression; gene ... See more keywords
Study of the Genetic Expression of Antiretroviral Restriction Factors and Acute Phase Proteins in Cattle Infected with Bovine Leukemia Virus
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens"
DOI: 10.3390/pathogens12040529
Abstract: The goal of this study was to analyze the genetic expression of antiretroviral restriction factors (ARF) and acute phase proteins (APP), as well as their correlation with proviral and viral loads in cattle with aleukemic… read more here.
Keywords: acute phase; antiretroviral restriction; genetic expression; expression ... See more keywords
Research on Cultivated Land Quality Restriction Factors Based on Cultivated Land Quality Level Evaluation
Sign Up to like & getrecommendations! Published in 2023 at "Sustainability"
DOI: 10.3390/su15097567
Abstract: Cultivated land quality is an essential agricultural resource and production element. To increase cultivated land quality in a targeted way, it is crucial to understand the features of regional elements that constrain its quality. In… read more here.
Keywords: cultivated land; land quality; restriction factors;
Feline APOBEC3s, Barriers to Cross-Species Transmission of FIV?
Sign Up to like & getrecommendations! Published in 2018 at "Viruses"
DOI: 10.3390/v10040186
Abstract: The replication of lentiviruses highly depends on host cellular factors, which defines their species-specific tropism. Cellular restriction factors that can inhibit lentiviral replication were recently identified. Feline immunodeficiency virus (FIV) was found to be sensitive… read more here.
Keywords: cross species; restriction factors; fiv; feline ... See more keywords
Mammalian and Avian Host Cell Influenza A Restriction Factors
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13030522
Abstract: The threat of a new influenza pandemic is real. With past pandemics claiming millions of lives, finding new ways to combat this virus is essential. Host cells have developed a multi-modular system to detect incoming… read more here.
Keywords: restriction factors; avian host; mammalian avian; influenza restriction ... See more keywords
HLA-A, HSPA5, IGFBP5 and PSMA2 Are Restriction Factors for Zika Virus Growth in Astrocytic Cells
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v15010097
Abstract: (1) Background: Zika virus (ZIKV), an arbo-flavivirus, is transmitted via Aeges aegyptii mosquitoes Following its major outbreaks in 2013, 2014 and 2016, WHO declared it a Public Health Emergency of International Concern. Symptoms of ZIKV… read more here.
Keywords: infection; astrocytic cells; zikv; zika virus ... See more keywords
T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the International AIDS Society"
DOI: 10.7448/ias.20.1.21865
Abstract: Introduction: Restriction factors (RFs) suppress HIV‐1 in cell lines and primary cell models. Hence, RFs might be attractive targets for novel antiviral strategies, but their importance for virus control in vivo is controversial. read more here.
Keywords: restriction; low cd2; restriction factors; cells low ... See more keywords