Articles with "restriction mimetics" as a keyword



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Glycolytic inhibition: an effective strategy for developing calorie restriction mimetics.

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Published in 2020 at "GeroScience"

DOI: 10.1007/s11357-020-00298-7

Abstract: Calorie restriction mimetics encompass a growing research field directed toward developing treatments that mimic the anti-aging effects of long-term calorie restriction without requiring a change in eating habits. A wide range of approaches have been… read more here.

Keywords: restriction; calorie restriction; restriction mimetics; strategy ... See more keywords
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Recent advances in the field of caloric restriction mimetics and anti-aging molecules

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Published in 2021 at "Ageing Research Reviews"

DOI: 10.1016/j.arr.2020.101240

Abstract: Caloric restriction (CR) mimetics are molecules that produce beneficial effects on health and longevity in model organisms and humans, without the challenges of maintaining a CR diet. Conventional CR mimetics such as metformin, rapamycin and… read more here.

Keywords: mimetics anti; aging molecules; restriction mimetics; caloric restriction ... See more keywords
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Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential.

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Published in 2019 at "Cell metabolism"

DOI: 10.1016/j.cmet.2019.01.018

Abstract: The increase in life expectancy has boosted the incidence of age-related pathologies beyond social and economic sustainability. Consequently, there is an urgent need for interventions that revert or at least prevent the pathogenic age-associated deterioration.… read more here.

Keywords: age; restriction mimetics; caloric restriction; mimetics age ... See more keywords