Restriction point regulation at the crossroads between quiescence and cell proliferation
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13867
Abstract: The coordination of cell proliferation with reversible cell cycle exit into quiescence is crucial for the development of multicellular organisms and for tissue homeostasis in the adult. The decision between quiescence and proliferation occurs at… read more here.
Keywords: cell proliferation; point; restriction point;
Runx3 plays a critical role in restriction-point and defense against cellular transformation
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2017.290
Abstract: The restriction (R)-point decision is fundamental to normal differentiation and the G1–S transition, and the decision-making machinery is perturbed in nearly all cancer cells. The mechanisms underlying the cellular context–dependent R-point decision remain poorly understood.… read more here.
Keywords: plays critical; critical role; point; runx3 plays ... See more keywords