Articles with "resulting reduced" as a keyword



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NUC-7738 regulates β-catenin signalling resulting in reduced proliferation and self-renewal of AML cells

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Published in 2022 at "PLOS ONE"

DOI: 10.1371/journal.pone.0278209

Abstract: Acute myeloid leukemia (AML) stem cells are required for the initiation and maintenance of the disease. Activation of the Wnt/β-catenin pathway is required for the survival and development of AML leukaemia stem cells (LSCs) and… read more here.

Keywords: aml; catenin signalling; aml cells; signalling resulting ... See more keywords