Articles with "results active" as a keyword



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Glycosylation of Erwinase results in active protein less recognized by antibodies

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Published in 2020 at "Biochemical Engineering Journal"

DOI: 10.1016/j.bej.2020.107750

Abstract: Abstract L-asparaginase (L-ASNase) is an important bacterial enzyme used as a biopharmaceutical to treat acute lymphoblastic leukemia (ALL). Side effects of L–ASNase therapy have been counteracted by polyethylene glycol (PEG)-modification of L-ASNase; however, immunogenicity of… read more here.

Keywords: erwinase results; glycosylation; results active; asnase ... See more keywords