Investigation of Discrepant MMR IHC and MSI PCR Test Results for Gynecologic Cancers using Next Generation Sequencing.
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DOI: 10.1016/j.humpath.2021.10.004
Abstract: Gynecologic cancers are routinely screened for DNA mismatch repair (MMR) gene mutations using immunohistochemistry (IHC) and/or PCR for MSI (microsatellite instability) to enable selection of immune checkpoint inhibitor therapy and screen for Lynch syndrome. The… read more here.
Keywords: gynecologic cancers; ihc msi; msi; next generation ... See more keywords