Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
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DOI: 10.1038/s41467-021-21820-1
Abstract: Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and the best-described monogenic cause of autism. CGG-repeat expansion in the FMR1 gene leads to FMR1 silencing, loss-of-expression of the Fragile X… read more here.
Keywords: results impaired; cognitive deficits; deficits mice; fmr1 ... See more keywords