A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.03.04.482974
Abstract: Resurgent currents (INaR) produced by voltage-gated sodium channels are required for many neurons to maintain high-frequency firing, and contribute to neuronal hyperexcitability and disease pathophysiology. Here we show, for the first time, that INaR can… read more here.
Keywords: sodium channels; voltage gated; type fhfs; resurgent currents ... See more keywords
Persistent and resurgent Na+ currents in vestibular calyx afferents.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neurophysiology"
DOI: 10.1152/jn.00124.2020
Abstract: Vestibular afferent neurons convey information from hair cells in vestibular end organs to central nuclei. These neurons can fire action potentials at high rates and firing patterns vary with the position of nerve terminal endings… read more here.
Keywords: mature; mature calyces; resurgent currents; calyx afferents ... See more keywords
A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels.
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.77558
Abstract: Resurgent currents (INaR) produced by voltage-gated sodium channels are required for many neurons to maintain high-frequency firing, and contribute to neuronal hyperexcitability and disease pathophysiology. Here we show, for the first time, that INaR can… read more here.
Keywords: sodium channels; resurgent currents; type fhfs; gated sodium ... See more keywords