Resveratrol prevents palmitic acid induced cardiomyocyte contractile impairment.
Sign Up to like & getrecommendations! Published in 2019 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2019-0051
Abstract: Short chain saturated fatty acids, especially palmitic acid (PA), contribute to cardiomyocyte lipotoxicity. This study tests the effects of PA on adult rat cardiomyocyte contractile function and proteins associated with calcium regulating cardiomyocyte contraction and… read more here.
Keywords: palmitic acid; resveratrol; resv; cardiomyocyte contractile ... See more keywords
Resveratrol Inhibits Periodontitis‐Related Bone Loss in Rats Subjected to Cigarette Smoke Inhalation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Periodontology"
DOI: 10.1902/jop.2017.170025
Abstract: BACKGROUND Alternative therapeutic approaches have been explored to modulate host response to periodontal disease. Knowledge of new strategies to treat periodontitis is particularly relevant in patients presenting augmented risk to periodontitis, such as smokers. The… read more here.
Keywords: resveratrol; resv; smoke inhalation; cigarette smoke ... See more keywords
Molecular design, synthesis and biological characterization of novel Resveratrol derivative as potential anticancer agent targeting NF-κB
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Biomedicine"
DOI: 10.32725/jab.2020.001
Abstract: Resveratrol (RESV), an anticancer nutraceutical compound, is known to show poor bioavailability inside the human body. Therefore, this study has designed multiple chemical analogs of RESV compound for improving its pharmacokinetic as well as its… read more here.
Keywords: resveratrol; resv; analog; resv compound ... See more keywords
Nano-Resveratrol: A Promising Candidate for the Treatment of Renal Toxicity Induced by Doxorubicin in Rats Through Modulation of Beclin-1 and mTOR
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.826908
Abstract: Background: Although doxorubicin (DXR) is one of the most used anticancer drugs, it can cause life-threatening renal damage. There has been no effective treatment for DXR-induced renal damage until now. Aim: This work aims at… read more here.
Keywords: dxr; nano resveratrol; resv; renal toxicity ... See more keywords
Natural Polyphenols May Normalize Hypochlorous Acid-Evoked Hemostatic Abnormalities in Human Blood
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DOI: 10.3390/antiox11040779
Abstract: During pathogen invasion, activated neutrophils secrete myeloperoxidase (MPO), which generates high local concentrations of hypochlorous acid (HOCl), a strong antimicrobial agent. Prolonged or uncontrolled HOCl production may, however, affect hemostasis, manifesting in inhibition of platelet… read more here.
Keywords: hypochlorous acid; may normalize; hocl; resv ... See more keywords