Synthesis and biological evaluation of resveratrol derivatives with anti‐breast cancer activity
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000044
Abstract: Resveratrol is a natural phytoestrogen produced by plants to protect themselves from injury, UV irradiation, and fungal attack. The main active structure is E‐resveratrol, which has many pharmacological activities. As the structure of resveratrol is… read more here.
Keywords: resveratrol; derivatives anti; breast cancer; resveratrol derivatives ... See more keywords
2‐Hydroxy‐4‐benzyloxylimine Resveratrol Derivatives as Potential Multifunctional Agents for the Treatment of Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2023 at "ChemMedChem"
DOI: 10.1002/cmdc.202200629
Abstract: A series of 2‐hydroxy‐4‐benzyloxylimine resveratrol derivatives was designed, synthesized and evaluated as multifunctional agents for the treatment of Parkinson's disease. The results revealed that most derivatives possessed good multifunctional activities. Among them, representative compound (E)‐5‐[(4‐fluorobenzyl)oxy]‐2‐{[(4‐hydroxyphenyl)imino]methyl}phenol… read more here.
Keywords: disease; benzyloxylimine resveratrol; parkinson disease; hydroxy benzyloxylimine ... See more keywords
Protective mechanisms of resveratrol derivatives against TNF‐&agr;‐induced inflammatory responses in rat mesangial cells
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2018.10.008
Abstract: Introduction: Resveratrol has been reported to alleviate inflammatory responses and oxidative stress in mesangial cells and in several types of renal injury in animal models. Previously, the active resveratrol derivatives from the roots of Vitis… read more here.
Keywords: inflammatory responses; tnf agr; mesangial cells; protective mechanisms ... See more keywords
Anti-Glycation and Anti-Aging Properties of Resveratrol Derivatives in the in-vitro 3D Models of Human Skin
Sign Up to like & getrecommendations! Published in 2022 at "Clinical, Cosmetic and Investigational Dermatology"
DOI: 10.2147/ccid.s364538
Abstract: Purpose Human skin undergoes modifications affecting its structural properties and barrier functions involved in protection against age-related damage. Glycation is a non-enzymatic reaction between macromolecules and sugars causing alterations to the elastic fibers and premature… read more here.
Keywords: anti aging; anti glycation; glycation; human skin ... See more keywords
Akt/mTOR Targeting Activity of Resveratrol Derivatives in Non-Small Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238268
Abstract: The Akt-mTOR signal is important for the survival and proliferation of cancer cells and has become an interesting drug target. In this study, five resveratrol derivatives were evaluated for anticancer activity and Akt/mTOR targeting activity… read more here.
Keywords: akt mtor; activity; cancer; resveratrol derivatives ... See more keywords
Therapeutic Versatility of Resveratrol Derivatives
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DOI: 10.3390/nu9111188
Abstract: Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the therapeutic application of resveratrol was encumbered for its low bioavailability. Therefore, many researchers focused… read more here.
Keywords: versatility resveratrol; therapeutic versatility; resveratrol; resveratrol derivatives ... See more keywords
The Bioactivities of Resveratrol and Its Naturally Occurring Derivatives on Skin
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Food and Drug Analysis"
DOI: 10.38212/2224-6614.1151
Abstract: Resveratrol has been extensively reported as a potential compound to treat some skin disorders, including skin cancer, photoaging, allergy, dermatitis, melanogenesis, and microbial infection. There has been an increasing interest in the discovery of cosmetic… read more here.
Keywords: resveratrol; bioactivities resveratrol; resveratrol naturally; occurring derivatives ... See more keywords