Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma.
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DOI: 10.1016/j.celrep.2019.01.109
Abstract: RET finger protein (RFP) forms a complex with histone deacetylase 1, resulting in aberrant deacetylation of H3K27ac and dysregulation of cis-regulatory elements. We evaluated the modulatory effects of RFP knockdown on cis-regulatory elements, gene expression,… read more here.
Keywords: glioblastoma; ret finger; cis regulatory; finger protein ... See more keywords