Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS.
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DOI: 10.1021/acsmedchemlett.8b00035
Abstract: Abdominal pain and abnormal bowel habits represent major symptoms for irritable bowel syndrome (IBS) patients that are not adequately managed. Although the etiology of IBS is not completely understood, many of the functions of the… read more here.
Keywords: gut restricted; ibs; ret kinase; kinase ... See more keywords