Contractile effects of retatrutide in isolated mouse atrial preparations
Sign Up to like & getrecommendations! Published in 2025 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-025-04335-0
Abstract: When retatrutide stimulates the glucagon receptor (GCGR), the glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR), and the glucagon-like peptide-1 receptor (GLP-1R), then 3′,5′cyclic adenosine monophosphate (cAMP) is increased. We tested the hypothesis that retatrutide like the… read more here.
Keywords: receptor; pce; isoprenaline; retatrutide ... See more keywords
Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
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DOI: 10.1038/s41591-024-03018-2
Abstract: Retatrutide is a novel triple agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1 and glucagon receptors. A 48-week phase 2 obesity study demonstrated weight reductions of 22.8% and 24.2% with retatrutide 8 and 12 mg,… read more here.
Keywords: steatotic liver; dysfunction associated; trial; retatrutide ... See more keywords
7792 Efficacy of Retatrutide for Weight Reduction and Its Cardiometabolic Effects Among Adults: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvae163.749
Abstract: Abstract Disclosure: D.C. Lopez: None. J.T. Pajimna: None. M.D. Milan: None. G.V. Jasul: None. G. Orpilla: None. I. Zapanta: None. B. Serquiña: None. G. Dychiao: None. Background: Obesity remains to be a global health challenge… read more here.
Keywords: none; meta analysis; retatrutide; weight reduction ... See more keywords