Efficient refolding of recombinant reteplase expressed in Escherichia coli strains using response surface methodology.
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DOI: 10.1016/j.ijbiomac.2020.07.183
Abstract: Reteplase is a deleted variant of human tissue plasminogen activator with a complex structure containing nine disulfide bonds. Reteplase is expressed as inclusion bodies in Escherichia coli and needs the additional step of refolding for… read more here.
Keywords: methodology; reteplase; escherichia coli; response surface ... See more keywords