The role of sphingolipids in endoplasmic reticulum stress
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13863
Abstract: The endoplasmic reticulum (ER) is an important intracellular compartment in eukaryotic cells and has diverse functions, including protein synthesis, protein folding, lipid metabolism and calcium homeostasis. ER functions are disrupted by various intracellular and extracellular… read more here.
Keywords: endoplasmic reticulum; role sphingolipids; reticulum stress; stress ... See more keywords
An NIR-Fluorophore-Based Therapeutic Endoplasmic Reticulum Stress Inducer.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201800475
Abstract: The endoplasmic reticulum (ER) stress signaling or unfolded protein response (UPR) is a common feature of many human diseases, including cancer. Excessive activation of ER stress directly induces cell death, holding a new promising strategy… read more here.
Keywords: endoplasmic reticulum; nir fluorophore; reticulum stress; stress ... See more keywords
Endoplasmic Reticulum Stress in Liver Diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32562
Abstract: The endoplasmic reticulum (ER) is an intracellular organelle that fosters the correct folding of linear polypeptides and proteins, a process tightly governed by the ER-resident enzymes and chaperones. Failure to shape the proper 3-dimensional architecture… read more here.
Keywords: endoplasmic reticulum; stress; liver; reticulum stress ... See more keywords
PM2.5 induces autophagy‐dependent ferroptosis by endoplasmic reticulum stress in SH‐SY5Y cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4439
Abstract: Fine particulate matter (PM2.5) has been a global environmental problem threatening public health in recent years. PM2.5 exposure was associated with an increased risk of neurodegenerative diseases related to neuronal apoptosis. Ferroptosis is a nonapoptotic… read more here.
Keywords: endoplasmic reticulum; ferroptosis; reticulum stress; pm2 ... See more keywords
The endoplasmic reticulum stress induced by tunicamycin affects the viability and autophagy activity of chondrocytes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23437
Abstract: Osteoarthritis (OA) is attributed to a reduction in chondrocytes within joint cartilage, and research has shown that endoplasmic reticulum (ER) stress and autophagy play important roles in the survival of chondrocytes. However, the relationship between… read more here.
Keywords: activity chondrocytes; endoplasmic reticulum; apoptosis; reticulum stress ... See more keywords
The role of endoplasmic reticulum stress in the regulation of long noncoding RNAs in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30846
Abstract: Cancer cells must overcome a variety of external and internal stresses to survive and proliferate. These unfavorable conditions include the accumulation of mutations, nutrient deficiency, oxidative stress, and hypoxia. These stresses can cause aggregation of… read more here.
Keywords: endoplasmic reticulum; stress; reticulum stress; long noncoding ... See more keywords
The double‐edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12288
Abstract: Sarcopenia is the age‐related degeneration characterized with the decline of skeletal muscle mass, strength, and function. The imbalance of protein synthesis and degradation which jeopardizes immune, hormone regulation, and muscle‐motor neuron connection is the main… read more here.
Keywords: sarcopenia; double edged; endoplasmic reticulum; reticulum stress ... See more keywords
Hydroquinone-induced endoplasmic reticulum stress affects TK6 cell autophagy and apoptosis via ATF6-mTOR.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23814
Abstract: Hydroquinone (HQ), one of the main active metabolites of benzene in vivo, 7is commonly used as a surrogate for benzene in in vitro studies and has been shown to be cytotoxic. The aim of this… read more here.
Keywords: endoplasmic reticulum; apoptosis; autophagy apoptosis; reticulum stress ... See more keywords
Neuroglobin protects against cerebral ischemia/reperfusion injury in rats by suppressing mitochondrial dysfunction and endoplasmic reticulum stress-mediated neuronal apoptosis through synaptotagmin-1.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23815
Abstract: Cerebral ischemia/reperfusion (I/R) injury remains a grievous health threat, and herein effective therapy is urgently needed. This study explored the protection of neuroglobin (Ngb) in rats with cerebral I/R injury. The focal cerebral I/R rat… read more here.
Keywords: endoplasmic reticulum; apoptosis; reticulum stress; injury rats ... See more keywords
Methods for Analyzing Endoplasmic Reticulum Stress in the Trabecular Meshwork of Glaucoma Models.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7407-8_12
Abstract: The pathological mechanisms underlying increased outflow resistance at the trabecular meshwork (TM) that is responsible for elevating intraocular pressure (IOP) have not been fully delineated. Recent studies have shown that progressive accumulation of misfolded proteins… read more here.
Keywords: trabecular meshwork; endoplasmic reticulum; reticulum stress; iop elevation ... See more keywords
Endoplasmic reticulum stress regulates tumor growth and anti-tumor immunity: a promising opportunity for cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-017-2019-6
Abstract: The endoplasmic reticulum (ER) stress is a cellular process that occurs as a consequence of several stress circumstances, such as the accumulation of unfolded proteins in the lumen of the ER or distinct insults that… read more here.
Keywords: endoplasmic reticulum; reticulum stress; stress; cancer immunotherapy ... See more keywords